Gene
ppp1r12c
- ID
- ZDB-GENE-010724-11
- Name
- protein phosphatase 1, regulatory subunit 12C
- Symbol
- ppp1r12c Nomenclature History
- Previous Names
-
- mypt2
- fi37e03
- wu:fc07c03
- wu:fi37e03
- zgc:152881
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have enzyme inhibitor activity and phosphatase regulator activity. Predicted to be involved in signal transduction. Predicted to localize to cytoplasm. Orthologous to human PPP1R12C (protein phosphatase 1 regulatory subunit 12C).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7159189 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR031775 | cGMP-dependent protein kinase, interacting domain |
| Family | IPR017401 | Protein phosphatase 1 regulatory subunit 12A/B/C |
| Family | IPR051226 | Protein Phosphatase 1 Regulatory Subunit |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | cGMP-dependent protein kinase, interacting domain | Protein Phosphatase 1 Regulatory Subunit | Protein phosphatase 1 regulatory subunit 12A/B/C |
|---|---|---|---|---|---|---|
|
UniProtKB:Q08BR9
|
672 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ppp1r12c-201
(1)
|
Ensembl | 3,549 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Woods, et al (2005. Genome Res. 15:1307-1314) and Rajarao, et al (2001. Genome Res. 11:1211-1220) reported this gene as the ortholog of human PPP1R12B. Subsequent analysis suggests that this gene is the ortholog of human PPP1R12C based on amino acid sequence similarity.